With research showing about 1 in 6 people worldwide who experience fatigue, it’s one of the most common self-reported symptoms that negatively impacts daily life — whether it’s constantly feeling tired, having zero motivation, experiencing mood swings that manifest as stress, anxiety, or depression, or having a hard time concentrating. Chronic fatigue — persistent fatigue that lasts for more than six months — can lead to more serious health conditions. If fatigue has you feeling drained, cannabis could give you the bright boost of refreshing energy you need to feel like yourself again. Sativa-dominant varieties are widely considered the best weed strains for fatigue, thanks to the blend of specific terpenes they typically contain known to produce bright and sunny effects. These are terpenes like citrusy limonene known to boost mood, as well as refreshing pinene that's said to increase mental clarity and focus. Terpinolene is another terpene known for delivering an uplifted calm that can be beneficial for those who suffer from fatigue that makes it hard to relax.
Best weed strains that may help with fatigue
Feeling mentally, physically, or emotionally exhausted? The right weed strain can brighten your vibe and put a pep in your step. Whether you need something to uplift the spirit, boost your mood, or deliver rocket-fuel like energy to make it through the day, there are certain cannabis cultivars that can help. Here you’ll find the best weed strains for fatigue, each with distinct effects known for their fresh, revitalizing energy.
Best weed for fatigue
From bright and sunny Sativas to hybrids that deliver an uplifting, energetic yet relaxing experience, these weed strains are all reported for fabulous fatigue-fighting effects.
Super Silver Haze
Super Silver Haze is a cannabis legend with an energizing and uplifting high that’s earned it multiple gold medals since it was created in the 1990s from a Haze, Northern Lights, and Skunk 1 cross. Its effects hit instantly, uplifting the spirits with its happy, energetic high. Super Silver Haze has a bright, revitalizing effect that will get you up and moving. You’ll find yourself energetic, talkative, and creative — all reasons why medical cannabis patients say this motivating sativa-dominant hybrid with around 21% THC is fabulous for managing daytime fatigue. Super Silver Haze has been referred to as “working man’s weed,” meaning it’s one of the best strains for fatigue that will help you power through your day.
Mind Flayer
Ideal for fighting fatigue towards the end of the day, Mind Flayer is a balanced hybrid that delivers a revitalizing cerebral boost followed by a sleepy, relaxed body high. Expect an uplifting head high that recharges your energy for a blissful giggly and creative experience. Be prepared to get real comfortable afterwards, as this initial cerebral boost becomes a soothing, somewhat sedating experience that will soon have you sleepy and ready for bed. Medical patients report the effects of this funky flavored blue cheese and sour citrus strain with 20% THC help fight both fatigue and insomnia — making Mind Flayer one of the best strains for fatigue to use late afternoons or early evenings when you need a bit of a cannabis boost help you finish off the day also known to deliver a solid night’s sleep.
Sour Diesel
Sour Diesel is a highly dominant sativa-hybrid (90/10) with an invigorating head and body high that makes it perfect for fighting fatigue. Widely considered one of the best sativas worldwide, Sour Diesel is legendary for its uplifting high and bright, happy buzz that leaves you blissfully euphoric, creatively inspired, and motivated to do just about anything. If you’re looking for one of the best strains for fatigue that will give you the get up and go energy you need to tackle your day, Sour Diesel is a highly cherished wake and bake strain perfect for promoting a positive mindset and putting a pep in your step.
Strawberry Amnesia
Strawberry Amnesia is a balanced sativa-dominant hybrid with a fresh strawberry flavor that delivers an energizing euphoric lift that’s perfect for fighting fatigue. Expect a blissfully happy and creative high when smoking on this 21% THC strain, where you’ll find yourself motivated by an upbeat energy that’s pure positive vibes. This high flying high winds down with a full-on sedative-like experience, with both mind and body wrapped in a heavily relaxed state of soothing calm. This blend of mental euphoria followed by a deep sense of relaxation makes Strawberry Amnesia one of the best strains for fatigue on days off or weekends when you need a boost of bright energy that’s followed by a chill relaxing vibe.
Green Crack
Green Crack is an all-star sativa dominant-hybrid that delivers a powerfully uplifting energy that’s made it famous. Originally called Green Cush when it was created in the 1990s, it was renamed by Snoop Dogg after the famous rapper experienced its intensely invigorating head high. You’ll find your energy blasts sky high after smoking on this sweet mango and citrus flavored strain, with an uplifting cerebral head high that will have you feeling focused, creative, and energized with massive amounts of motivation that will inspire you to get things done. This supercharged strain won Best Sativa at the 2015 Denver High Times Cannabis Cup for a reason — it’s fabulous for eliminating fatigue and delivering a vibrant burst of energy that keeps you upbeat and moving.